If you are building software around genomic testing, the first trap is treating a sequencing order like any other lab order. A requisition-to-report workflow has distinct handoffs (accessioning, library prep, sequencing, secondary analysis, variant interpretation, clinician sign-off) and each one needs its own audit trail. Generic EHR lab modules usually model only the first and last step, so the middle ends up in spreadsheets and email. https://nonstopio.com/genomics/

The second gap is cascade screening. Once a pathogenic variant is confirmed, the system has to track which relatives should be offered testing and what consent exists. That is pedigree logic, not order logic. We documented how we handle LIMS integration, variant interpretation and cascade screening in NonStopio's genomics team, which is a useful reference if you are scoping something similar.