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Investment Opportunities in Women’s Digital Health

Digital health is a broad term that refers to the utilization of communication and information technologies to manage, track, and improve the overall healthcare delivery system.

Owing to the potential of digital technology to optimize patient healthcare and the development of pharmaceuticals, the digital healthcare industry has witnessed significant rise in investments in the past decade, including in the women’s digital health space. It is worth noting that the digital health initiative is mainly focused on developing and providing a range of easy-to-use and innovative tools to patients, scientists / researchers, healthcare professionals, and other industry stakeholders for better health management. A significant increase in adoption of digital solutions has been witnessed in this field, especially after the outbreak of pandemic.
Over the years, several initiatives have been undertaken by various industry stakeholders across the globe to promote digital health solutions and their applications. For instance, in 2019, the Preventive Healthcare tool was launched by Facebook to connect people to different health resources, enabling its users to set reminders for checkups, schedule tests and track their past activity.

Women’s Digital Health
Women’s digital health or FemTech is a broad industry that offers various products, services, diagnostic tools, wearable devices, software, applications and technologies in order to address the issues associated with women’s health, including menstrual, reproductive, sexual, maternity, and menopause disorders. Since it is primarily focused on women’s healthcare, it has been termed as Female Technology or FemTech.
In the past few years, several investments have been made by various institutional investors in the companies associated with women’s digital health sector. For instance, in April 2022, USD 28.5 million was raised by Evernow in venture series A for re-defining the menopause treatment. Additionally, in February 2022, USD 15 million was raised by Ro in venture series E to expand its direct-to-patient healthcare model.

Key Application Areas of FemTech Industry
The FemTech industry provides an opportunity for better self-management, enabling and empowering women to be more in control of their own health and wellbeing.

Future Perspectives
Owing to the increased adoption rate of digital solutions and rise in the demand for telehealth services, the companies involved in the women’s digital health domain have witnessed a surge in the investment activity. Subsequently, capital investments worth more than USD 3 billion have been made in this domain, over the past few years. Nearly 90% of the capital invested in the companies has, so far, come in from venture capital funding; some companies have already gone public. Moreover, there is a high unmet need in certain areas, such as management of mental health, disease conditions, such as PCOS, endometriosis and disease which have high prevalence among women. In order to identify the gaps and unmet needs, it is important to develop customized and focused solutions, and establish policies that can help in increasing awareness about women’s health. Given the potential of digital health solutions, with the development of affordable and accessible digital technologies, the healthcare service industry is expected to witness noteworthy growth in the coming years. Furthermore, taking into consideration the ongoing efforts to develop solutions for existing unmet needs, we expect the women’s digital health market to present numerous lucrative investment opportunities in the future.
For additional details, please visit https://www.rootsanalysis.com/....blog/womens-digital-

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About Roots Analysis
Roots Analysis is a global leader in the pharma / biotech market research. Having worked with over 750 clients worldwide, including Fortune 500 companies, start-ups, academia, venture capitalists and strategic investors for more than a decade, we offer a highly analytical / data-driven perspective to a network of over 450,000 senior industry stakeholders looking for credible market insights.

Contact:
Ben Johnson
+1 (415) 800 3415
Ben.johnson@rootsanalysis.com

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Genotoxicity Testing: Unlocking the Future Safety Assessment Opportunities

Genotoxicity testing refers to the evaluation of detrimental effects of chemical or physical agents on the genetic processes and related hereditary material of living cells.

On the other hand, mutagenicity is the process of inducing irreversible and transmissible alterations in the genetic material of organisms either spontaneously or through mutagenic activity.

Disruption of the integrity and function of DNA at the gene or chromosomal level can lead to heritable mutations, resulting in genetic disorders, birth abnormalities, or cancer. Potential targets for DNA damage include somatic cells (confined to the exposed generation), germinal cells (potentially inherited effects), and mitochondria (detrimental to the exposed individual and progeny via maternal inheritance).

Detrimental Effects of Genotoxins and Mutagens
Genotoxins are chemical substances or radiations which causes genotoxicity leading to DNA or chromosomal damage, further leading to mutations. In eukaryotic organisms, damage to genetic material of somatic cell can lead to malignancy (cancer) whereas genetic damage to germ cells can result in heritable mutations that induce birth defects.

Mechanism of Genotoxicity / Mutagenicity
The interaction of genotoxins / mutagens with the structure of DNA causes damage to the genetic material. These genotoxic / mutagenic substances interact with the DNA structure at a specific base sequence, inducing deletion, mis-segregation, or non-disjunction, resulting in damage and mutation.

Techniques Used for Genotoxicity / Mutagenicity Testing
Genotoxins can be classified based on their effects into the following types:
• Carcinogens: These have the ability to cause cancer. Examples – Asbestos, Benzene, Vinyl chloride and Carbon tetrachloride
• Mutagens: These can induce mutations in the genetic material of an organism. Examples – Chloroform, Ethylene oxide, and Lead
• Teratogens: These agents cause birth defects, abnormalities, or developmental problems in the offspring. Examples – Carbon monoxide, Lead and Xylene

GENE MUTATION
Ames Test: It is used to evaluate an agent’s mutagenic potential by reversing mutations in the tester mutant bacteria (E. coli, Salmonella typhi), as well as its ability to synthesize an essential amino acid required for growth
MLA / HPRT: It is used to evaluate an agent’s mutagenic potential by reversing mutations in the tester mutant bacteria (E. coli, Salmonella typhi), as well as its ability to synthesize an essential amino acid required for growth
Mutation Assay: Transgenic rodent somatic and germ cell gene mutation assay specifies an in vivo assay that perceives gene mutation causing agents. Transgenic mice or rats with several copies of chromosomally integrated plasmids or phage shuttle vectors are employed in this test.
DNA DAMAGES
Comet Assay: The comet assay, also known as single cell gel electrophoresis (SCGE), is an efficient technique for identifying DNA strand breaks in a cell. It is used in molecular epidemiology, genotoxicity testing, and basic studies on DNA damage and repair.
CHROMOSOMAL DAMAGES
Chromosomal Aberration Test: The comet assay, also known as single cell gel electrophoresis (SCGE), is an efficient technique for identifying DNA strand breaks in a cell. It is used in molecular epidemiology, genotoxicity testing, and basic studies on DNA damage and repair.
Micronucleus Test: The micronucleus identifies chemicals (liquid or solid) that lead to cytogenetic damage, resulting in the formation of micronuclei containing complete or lagging chromosomal segments.
Applications of Genotoxicity / Mutagenicity
Genotoxicity testing and mutagenicity testing can be employed in a wide range of industries. It detects the potential long-term effects of the compounds which are marketed without knowing their ability to affect human and environmental health.

For additional details, please visit https://www.rootsanalysis.com/....blog/genotoxicity-mu

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1. Quantum Computing in Drug Discovery Services Market : - Industry Trends and Global Forecasts, 2023-2035
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About Roots Analysis
Roots Analysis is a global leader in the pharma / biotech market research. Having worked with over 750 clients worldwide, including Fortune 500 companies, start-ups, academia, venture capitalists and strategic investors for more than a decade, we offer a highly analytical / data-driven perspective to a network of over 450,000 senior industry stakeholders looking for credible market insights.

Contact:
Ben Johnson
+1 (415) 800 3415
Ben.johnson@rootsanalysis.com

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